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In particular, previously common terms such as office girl are no longer widely used.

Conversely, in certain cultures which link family honor with female virginity, the word girl is still used to refer to a never-married woman; in this sense it is used in a fashion roughly analogous to the obsolete English maid or maiden.

(For other ways in which men commonly differ physically from women, see man.) During early fetal development, embryos of both sexes appear gender-neutral.

As in cases without two sexes, such as species that reproduce asexually, the gender-neutral appearance is closer to female than to male.

Most women have the karyotype 46, XX, but around one in a thousand will be 47, XXX, and one in 2500 will be 45, X.